I cannot say that the word "best" has ever come to mind as I drive down an interstate, but I would agree that some are better than others. No one would know better than truck drivers that just ranked the best interstates in America and one that crosses Missouri was named one of the best.
There's something mysterious happening in the fields next to I-44 in Missouri. What looks like crop circles are visible from above. Is the work of aliens? Not exactly.